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The proposed standard aims at describing a method to analyze 57 chemically defined suspected allergens (some of them existing under several isomeric forms or as mixtures) in ready to inject fragrance and raw material samples according to the SCCS opinion. (SCCS/1459/11).
This new analytical method uses gas chromatography and mass spectrometry (GC-MS) to detect and to quantify the 57 fragrance substances and their relevant isomers at a concentration higher than 0.0002% (2 mg/kg) in ready to inject fragrance and raw material samples. Making this method available will allow the screening of (complex) ready to inject fragrance and raw material samples to be undertaken for the presence of any of those chemically defined suspected allergens. It will therefore be a basis for the calculation of adequate information to the cosmetics industry in order to provide adequate consumer information. The present analytical method uses GC-MS by combination of two GC columns of different polarity with a dedicated methodology for quantitation.
Reģistrācijas numurs (WIID)
64970
Darbības sfēra
The proposed standard aims at describing a method to analyze 57 chemically defined suspected allergens (some of them existing under several isomeric forms or as mixtures) in ready to inject fragrance and raw material samples according to the SCCS opinion. (SCCS/1459/11).
This new analytical method uses gas chromatography and mass spectrometry (GC-MS) to detect and to quantify the 57 fragrance substances and their relevant isomers at a concentration higher than 0.0002% (2 mg/kg) in ready to inject fragrance and raw material samples. Making this method available will allow the screening of (complex) ready to inject fragrance and raw material samples to be undertaken for the presence of any of those chemically defined suspected allergens. It will therefore be a basis for the calculation of adequate information to the cosmetics industry in order to provide adequate consumer information. The present analytical method uses GC-MS by combination of two GC columns of different polarity with a dedicated methodology for quantitation.
